We travelled as a group of 4 adults and we all loved the relaxed feel and atmosphere at The Hotel San Marco. The San Marco provides an excellent holiday base in easy reach of the City's main tourist attractions. We walked everywhere due to the fantastic weather, but both tram stops and the metro are also nearby. The hotel is furnished in a minimalistic, modern, clutter free (IKEA type) style and our rooms were clean, spacious and bright. The breakfast buffet was typically continental i.e. breads, meats and cheeses etc.
Local restaurants were excellent and good value, with a particular mention for 'The Legenda' only a few yards from the hotel.
Hotel staff were helpful and polite and we would all be delighted to make a return visit.
Watch out for the lack of hot water for a shower first thing in the morning though, as this was the only slight irritation we experienced, otherwise it was perfect for a relaxed, informal and relatively low cost stay.
Oh and be careful crossing the roads in Prague, if the trams don't get you the manic drivers will !